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Thalassemia

Professional Name Thalassemia

Summary

Thalassemia is a hereditary blood disease, which is also a kind of anemia. It can be mild or severe. Some mild thalassemia can be treated by medications or occasional blood transfusion, but some severe thalassemia will need further medical treatment like stem cell transplant.

Description

Thalassemia is a hereditary anemia which can result in lower amounts of hemoglobin and red blood cells. There are several kinds of thalassemia. They include Mediterranean anemia, Cooley's anemia, alpha-thalassemia and beta-thalassemia, Cooley's anemia.

Occurrence + Symptoms

Anemia is caused by a lower amount of red blood cells or a lower amount of hemoglobin in red blood cells. Thalassemia is a kind of anemia. It is inherited and may cause the body to make fewer healthy red blood cells and less hemoglobin than normal. Thalassemia can be mild or severe. Some people have no symptoms or mild anemia, and the common symptoms are fatigue, weakness, pale appearance, jaundice, dark urine and so on. But some have severe anemia such as Cooley's anemia. It usually appears in the early time of life, mostly in the first two years. People with it may have severe anemia, slowed growth and delayed puberty, and problems with the spleen, liver, heart, or bones.

Consequences + Treatment

The treatments of thalassemia will depend on the severity. For people with mild anemia, an occasional transfusion of blood can be enough for them to improve the condition, and some people with beta-thalassemia may need treatment for iron overload, medication as deferasirox can help remove the excess iron. For severe thalassemia, frequent blood transfusion and stem cell transplant will be needed.

Possible symptoms of the disease:

pallor, paleness, yellowish discoloration of the skin
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